• Supai, arguably the most isolated towns in the USA. In fact, no there are no transportation to the small town. And the best way to get there is by foot, mule or horse (for those more demanding helicopters). The reason is none other than its complicated geographical location: Supai is located at the bottom of the Grand Canyon, within the Havasupai Indian Reservation, and nestled between the hundreds of feet high of Grand Canyon walls.
  • In Supai there are 136 housing units, and about 423 inhabitants according to the 1990 census, and in 2000, the census recorded no inhabitant wrongly. Of course in Supai, there is no cars, and the appearance is something like a rural village, which currently is the main source of tourism revenue, with enough attractions that only seeing is believing. Among them, a nearby waterfall with blue water and red earth.

From:  VisitingParadise.com